Drug interactions
Nicardipine + Prednisone
Severity: Minor
Nicardipine and Prednisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nicardipine inhibits CYP3A4 and may modestly raise corticosteroid exposure, while prednisone is only a weak CYP3A4 inducer. No clinically important change in effect of either drug is well documented.
What this interaction means in plain words
Nicardipine and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nicardipine belongs to Cardiovascular; Prednisone belongs to Endocrine.
Why it happens
Possible minor CYP3A4 and P-glycoprotein effects altering corticosteroid or nicardipine exposure.
What to do
No routine adjustment; monitor blood pressure and corticosteroid adverse effects during long-term co-therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Nicardipine
Frequently asked questions
Can I take Nicardipine with Prednisone?
MediHelp rates the interaction as minor. Nicardipine and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nicardipine inhibits CYP3A4 and may modestly raise corticosteroid exposure, while prednisone is only a weak CYP3A4 inducer. No clinically important change in effect of either drug is well documented.
How serious is the interaction between Nicardipine and Prednisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment; monitor blood pressure and corticosteroid adverse effects during long-term co-therapy.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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