Drug interactions
Nisoldipine + Terazosin
Severity: Moderate
Nisoldipine and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination of an alpha-blocker and a dihydropyridine calcium channel blocker produces additive blood pressure lowering. Symptoms may include dizziness, orthostatic hypotension and peripheral edema.
What this interaction means in plain words
Nisoldipine and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nisoldipine belongs to Cardiovascular; Terazosin belongs to Genitourinary.
Why it happens
Additive vasodilation through alpha-1 blockade and calcium channel blockade.
What to do
Monitor blood pressure when either drug is started or titrated, and reduce the dose if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Nisoldipine
- Itraconazole + Nisoldipine Contraindicated
- Ketoconazole + Nisoldipine Contraindicated
- Apalutamide + Nisoldipine Major
- Carbamazepine + Nisoldipine Major
- Chloramphenicol + Nisoldipine Major
- Clarithromycin + Nisoldipine Major
Frequently asked questions
Can I take Nisoldipine with Terazosin?
MediHelp rates the interaction as moderate. Nisoldipine and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The combination of an alpha-blocker and a dihydropyridine calcium channel blocker produces additive blood pressure lowering. Symptoms may include dizziness, orthostatic hypotension and peripheral edema.
How serious is the interaction between Nisoldipine and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when either drug is started or titrated, and reduce the dose if hypotension develops.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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