Drug interactions
Olanzapine + Tiotropium-olodaterol
Severity: Minor
Olanzapine and Tiotropium-olodaterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olanzapine has anticholinergic properties that may add to tiotropium and cause dry mouth, constipation, urinary retention and tachycardia. Cardiovascular effects with olodaterol such as tachycardia are also possible.
What this interaction means in plain words
Olanzapine and Tiotropium-olodaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Olanzapine belongs to Central Nervous System; Tiotropium-olodaterol belongs to Respiratory.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for anticholinergic effects, especially in older patients or those with glaucoma or urinary retention. No dose adjustment is usually required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tiotropium-olodaterol
Other interactions of Olanzapine
Frequently asked questions
Can I take Olanzapine with Tiotropium-olodaterol?
MediHelp rates the interaction as minor. Olanzapine and Tiotropium-olodaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Olanzapine has anticholinergic properties that may add to tiotropium and cause dry mouth, constipation, urinary retention and tachycardia. Cardiovascular effects with olodaterol such as tachycardia are also possible.
How serious is the interaction between Olanzapine and Tiotropium-olodaterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects, especially in older patients or those with glaucoma or urinary retention. No dose adjustment is usually required.
What other medicines interact with Tiotropium-olodaterol?
MediHelp also lists interactions of Tiotropium-olodaterol with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Tiotropium-olodaterol page.
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