Drug interactions
Olodaterol inhaled + Risperidone
Severity: Moderate
Olodaterol inhaled and Risperidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Risperidone can prolong the QT interval, and beta2-agonists can cause hypokalemia, tachycardia and QT prolongation. Inhaled olodaterol has low systemic exposure, so the risk is mostly relevant at high doses or in patients with cardiac risk factors.
What this interaction means in plain words
Olodaterol inhaled and Risperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta2-mediated hypokalemia and tachycardia.
What to do
Use olodaterol at the labeled dose and monitor ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Report palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Risperidone
- Ibutilide + Risperidone Contraindicated
- Risperidone + Vandetanib Contraindicated
- Adagrasib + Risperidone Major
- Amiodarone + Risperidone Major
- Amisulpride + Risperidone Major
- Amoxapine + Risperidone Major
Frequently asked questions
Can I take Olodaterol inhaled with Risperidone?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Risperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Risperidone can prolong the QT interval, and beta2-agonists can cause hypokalemia, tachycardia and QT prolongation. Inhaled olodaterol has low systemic exposure, so the risk is mostly relevant at high doses or in patients with cardiac risk factors.
How serious is the interaction between Olodaterol inhaled and Risperidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use olodaterol at the labeled dose and monitor ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Report palpitations or syncope.
What other medicines interact with Risperidone?
MediHelp also lists interactions of Risperidone with, for example, Ibutilide, Vandetanib, Adagrasib. The full list is on the Risperidone page.
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