Drug reference
risperidone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic (atypical))
Mechanism of action
Has high affinity for serotonin type 2 (5-HT2) receptors; binds to dopamine D2 receptors with 20 times lower affinity than that for 5-HT2 receptors; antagonizes alpha1-adrenergic, alpha2-adrenergic, and histaminergic receptors; has moderate affinity for serotonin type 1 (5-HT1C, 5-HT1D, 5-HT1A) receptors; has weak affinity for dopamine D1 receptors
Common side effects
- Insomnia
- Agitation
- Somnolence
- Headache
- Fatigue
- Rhinitis
- Anxiety
Known interactions (4)
- amisulpride + risperidone Major
- cabergoline + risperidone Major
- dopamine + risperidone Moderate
- risperidone + sertraline Moderate
Related conditions
Frequently asked questions
What drug class is risperidone?
risperidone belongs to: Central Nervous System.
How does risperidone work?
Has high affinity for serotonin type 2 (5-HT2) receptors; binds to dopamine D2 receptors with 20 times lower affinity than that for 5-HT2 receptors; antagonizes alpha1-adrenergic, alpha2-adrenergic, and histaminergic receptors; has moderate affinity for serotonin type 1 (5-HT1C, 5-HT1D, 5-HT1A) receptors; has weak affinity for dopamine D1 receptors
What are the common side effects of risperidone?
Insomnia, Agitation, Somnolence, Headache, Fatigue, Rhinitis, Anxiety
Which drugs interact with risperidone?
amisulpride, cabergoline, dopamine, sertraline
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