Drug interactions
Oritavancin + Quinidine
Severity: Minor
Oritavancin and Quinidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oritavancin is a weak CYP3A4 inducer and may slightly lower quinidine concentrations. The clinical effect is probably small but matters for a narrow-therapeutic-index drug.
What this interaction means in plain words
Oritavancin and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oritavancin belongs to Anti Bacterial; Quinidine belongs to Anti Parasitic.
Why it happens
Oritavancin weakly induces CYP3A4, modestly increasing quinidine metabolism.
What to do
Monitor clinical response and quinidine levels if used together. Dose changes are rarely needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Oritavancin
- Heparin + Oritavancin Contraindicated
- Oritavancin + Warfarin Moderate
- Carbamazepine + Oritavancin Minor
- Cyclosporin + Oritavancin Minor
- Ethosuximide + Oritavancin Minor
- Flecainide + Oritavancin Minor
Frequently asked questions
Can I take Oritavancin with Quinidine?
MediHelp rates the interaction as minor. Oritavancin and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer and may slightly lower quinidine concentrations. The clinical effect is probably small but matters for a narrow-therapeutic-index drug.
How serious is the interaction between Oritavancin and Quinidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response and quinidine levels if used together. Dose changes are rarely needed.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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