Drug interactions
Osilodrostat + Telavancin
Severity: Moderate
Osilodrostat and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Osilodrostat can prolong the QT interval and telavancin may add to the effect. This may raise the risk of torsades de pointes, especially with hypokalemia or hypomagnesemia, which can occur in Cushing's disease.
What this interaction means in plain words
Osilodrostat and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Osilodrostat belongs to Endocrine; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation.
What to do
Obtain a baseline ECG and correct potassium and magnesium before and during therapy. Monitor ECG while both are used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Osilodrostat
Frequently asked questions
Can I take Osilodrostat with Telavancin?
MediHelp rates the interaction as moderate. Osilodrostat and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Osilodrostat can prolong the QT interval and telavancin may add to the effect. This may raise the risk of torsades de pointes, especially with hypokalemia or hypomagnesemia, which can occur in Cushing's disease.
How serious is the interaction between Osilodrostat and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct potassium and magnesium before and during therapy. Monitor ECG while both are used.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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