Drug interactions
Oxazepam + Papaverine
Severity: Minor
Oxazepam and Papaverine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Papaverine can cause mild sedation and drowsiness, and may add to the effects of oxazepam. The interaction is generally of limited clinical significance.
What this interaction means in plain words
Oxazepam and Papaverine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oxazepam belongs to Central Nervous System; Papaverine belongs to Cardiovascular.
Why it happens
Possible additive sedation; the mechanism is not well established.
What to do
No dose change is normally needed; advise patients to watch for excess drowsiness and avoid driving if affected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxazepam
- Calcium / magnesium / potassium / sodium oxybates + Oxazepam Contraindicated
- Oxazepam + Sodium oxybate Contraindicated
- Alfentanil + Oxazepam Major
- Amobarbital + Oxazepam Major
- Baclofen + Oxazepam Major
- Belladonna and opium + Oxazepam Major
Other interactions of Papaverine
- Givinostat + Papaverine Major
- Bretylium + Papaverine Moderate
- Calcium / magnesium / potassium / sodium oxybates + Papaverine Moderate
- Carbidopa-entacapone-levodopa + Papaverine Moderate
- Carbidopa-levodopa + Papaverine Moderate
- Carbidopa + Papaverine Moderate
Frequently asked questions
Can I take Oxazepam with Papaverine?
MediHelp rates the interaction as minor. Oxazepam and Papaverine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Papaverine can cause mild sedation and drowsiness, and may add to the effects of oxazepam. The interaction is generally of limited clinical significance.
How serious is the interaction between Oxazepam and Papaverine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is normally needed; advise patients to watch for excess drowsiness and avoid driving if affected.
What other medicines interact with Oxazepam?
MediHelp also lists interactions of Oxazepam with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Oxazepam page.
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