Drug interactions
Pindolol + Ropivacaine
Severity: Minor
Pindolol and Ropivacaine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ropivacaine can cause hypotension and bradycardia, particularly with neuraxial blocks or when systemic levels are high. Pindolol may add to these effects.
What this interaction means in plain words
Pindolol and Ropivacaine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive negative chronotropic and hypotensive effects from beta blockade and local anesthetic sodium channel blockade.
What to do
Monitor heart rate and blood pressure during and after the block and use the lowest effective ropivacaine dose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ropivacaine
- Bupivacaine implant + Ropivacaine Major
- Bupivacaine liposome + Ropivacaine Major
- Amlodipine-benazepril + Ropivacaine Moderate
- Benazepril + Ropivacaine Moderate
- Captopril-hydrochlorothiazide + Ropivacaine Moderate
- Captopril + Ropivacaine Moderate
Frequently asked questions
Can I take Pindolol with Ropivacaine?
MediHelp rates the interaction as minor. Pindolol and Ropivacaine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ropivacaine can cause hypotension and bradycardia, particularly with neuraxial blocks or when systemic levels are high. Pindolol may add to these effects.
How serious is the interaction between Pindolol and Ropivacaine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure during and after the block and use the lowest effective ropivacaine dose.
What other medicines interact with Ropivacaine?
MediHelp also lists interactions of Ropivacaine with, for example, Bupivacaine implant, Bupivacaine liposome, Amlodipine-benazepril. The full list is on the Ropivacaine page.
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