Drug interactions
Pirbuterol + Propylhexedrine
Severity: Moderate
Pirbuterol and Propylhexedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propylhexedrine is a sympathomimetic nasal decongestant, and systemic absorption can add to the cardiovascular stimulation of pirbuterol. Palpitations, tachycardia and raised blood pressure may occur.
What this interaction means in plain words
Pirbuterol and Propylhexedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive sympathomimetic effects.
What to do
Monitor heart rate and blood pressure, and limit decongestant use to labeled doses. Avoid in patients with significant cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Propylhexedrine
- Isocarboxazid + Propylhexedrine Contraindicated
- Phenelzine + Propylhexedrine Contraindicated
- Linezolid + Propylhexedrine Major
- Propylhexedrine + Selegiline Major
- Propylhexedrine + Tranylcypromine Major
- Adrenaline-articaine + Propylhexedrine Moderate
Frequently asked questions
Can I take Pirbuterol with Propylhexedrine?
MediHelp rates the interaction as moderate. Pirbuterol and Propylhexedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Propylhexedrine is a sympathomimetic nasal decongestant, and systemic absorption can add to the cardiovascular stimulation of pirbuterol. Palpitations, tachycardia and raised blood pressure may occur.
How serious is the interaction between Pirbuterol and Propylhexedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure, and limit decongestant use to labeled doses. Avoid in patients with significant cardiovascular disease.
What other medicines interact with Propylhexedrine?
MediHelp also lists interactions of Propylhexedrine with, for example, Isocarboxazid, Phenelzine, Linezolid. The full list is on the Propylhexedrine page.
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