Drug interactions
Pitavastatin + Stiripentol
Severity: Minor
Pitavastatin and Stiripentol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Stiripentol may modestly raise pitavastatin levels, with a possible increase in muscle-related adverse effects.
What this interaction means in plain words
Pitavastatin and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Pitavastatin belongs to Cardiovascular; Stiripentol belongs to Central Nervous System.
Why it happens
Stiripentol inhibits BCRP and CYP2C8, which may reduce pitavastatin efflux and clearance.
What to do
Monitor for myalgia and reduce the pitavastatin dose if adverse effects occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pitavastatin
- Cyclosporine + Pitavastatin Contraindicated
- Cyclosporin + Pitavastatin Contraindicated
- Erythromycin base + Pitavastatin Major
- Erythromycin ethylsuccinate + Pitavastatin Major
- Erythromycin lactobionate + Pitavastatin Major
- Erythromycin stearate + Pitavastatin Major
Other interactions of Stiripentol
Frequently asked questions
Can I take Pitavastatin with Stiripentol?
MediHelp rates the interaction as minor. Pitavastatin and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stiripentol may modestly raise pitavastatin levels, with a possible increase in muscle-related adverse effects.
How serious is the interaction between Pitavastatin and Stiripentol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for myalgia and reduce the pitavastatin dose if adverse effects occur.
What other medicines interact with Pitavastatin?
MediHelp also lists interactions of Pitavastatin with, for example, Cyclosporine, Cyclosporin, Erythromycin base. The full list is on the Pitavastatin page.
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