Drug interactions
Potassium iodide + Ramipril
Severity: Moderate
Potassium iodide and Ramipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies potassium, and ramipril reduces renal potassium excretion, so serum potassium can rise. Hyperkalemia is more likely with renal impairment, diabetes or prolonged use.
What this interaction means in plain words
Potassium iodide and Ramipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Potassium iodide belongs to Endocrine; Ramipril belongs to Cardiovascular.
Why it happens
ACE inhibition lowers aldosterone-mediated renal potassium excretion, while potassium iodide adds a potassium load.
What to do
Monitor serum potassium during prolonged or high-dose potassium iodide use, and stop or reduce it if hyperkalemia develops. Short courses at standard doses usually need little action.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ramipril
- Aliskiren + Ramipril Contraindicated
- Protein a column + Ramipril Contraindicated
- Ramipril + Sacubitril / valsartan Contraindicated
- Ramipril + Sacubitril-valsartan Contraindicated
- Amifostine + Ramipril Major
- Amiloride + Ramipril Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Potassium iodide with Ramipril?
MediHelp rates the interaction as moderate. Potassium iodide and Ramipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Potassium iodide supplies potassium, and ramipril reduces renal potassium excretion, so serum potassium can rise. Hyperkalemia is more likely with renal impairment, diabetes or prolonged use.
How serious is the interaction between Potassium iodide and Ramipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium during prolonged or high-dose potassium iodide use, and stop or reduce it if hyperkalemia develops. Short courses at standard doses usually need little action.
What other medicines interact with Ramipril?
MediHelp also lists interactions of Ramipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Ramipril page.
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