Drug interactions
Potassium iodide + Tolmetin
Severity: Minor
Potassium iodide and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies potassium, and NSAIDs can reduce renal potassium excretion. Hyperkalemia is possible in patients with renal impairment or other risk factors, though the potassium load from usual iodide doses is small.
What this interaction means in plain words
Potassium iodide and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Potassium iodide belongs to Endocrine; Tolmetin belongs to Musculoskeletal.
Why it happens
NSAIDs lower renin and aldosterone via reduced prostaglandin synthesis, decreasing potassium excretion, on top of the added potassium load.
What to do
Check serum potassium in patients with renal impairment, diabetes or other potassium-raising drugs. No action is generally needed otherwise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Potassium iodide with Tolmetin?
MediHelp rates the interaction as minor. Potassium iodide and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Potassium iodide supplies potassium, and NSAIDs can reduce renal potassium excretion. Hyperkalemia is possible in patients with renal impairment or other risk factors, though the potassium load from usual iodide doses is small.
How serious is the interaction between Potassium iodide and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium in patients with renal impairment, diabetes or other potassium-raising drugs. No action is generally needed otherwise.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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