Drug interactions
Potassium iodide + Valsartan
Severity: Moderate
Potassium iodide and Valsartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide contains potassium that may add to the hyperkalemic effect of valsartan. The risk is mainly with prolonged or repeated dosing and impaired renal function.
What this interaction means in plain words
Potassium iodide and Valsartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Potassium iodide belongs to Endocrine; Valsartan belongs to Cardiovascular.
Why it happens
Added potassium load combined with ARB-mediated aldosterone suppression reducing potassium excretion.
What to do
Monitor serum potassium and renal function when potassium iodide is used repeatedly or long term. Single short-course use generally needs no change.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Valsartan
- Aliskiren + Valsartan Contraindicated
- Sparsentan + Valsartan Contraindicated
- Aldesleukin + Valsartan Major
- Amifostine + Valsartan Major
- Amiloride + Valsartan Major
- Amlodipine-benazepril + Valsartan Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Potassium iodide with Valsartan?
MediHelp rates the interaction as moderate. Potassium iodide and Valsartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Potassium iodide contains potassium that may add to the hyperkalemic effect of valsartan. The risk is mainly with prolonged or repeated dosing and impaired renal function.
How serious is the interaction between Potassium iodide and Valsartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function when potassium iodide is used repeatedly or long term. Single short-course use generally needs no change.
What other medicines interact with Valsartan?
MediHelp also lists interactions of Valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Valsartan page.
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