Drug interactions
propafenone + ritonavir
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ propafenone → proarrhythmia.
Mechanism of action
CYP3A4/2D6 inhibition.
Clinical management
Avoid or monitor closely with ECG.
Drug reference
References
Frequently asked questions
Can I take propafenone with ritonavir?
The interaction is rated: Major. ↑ propafenone → proarrhythmia.
How serious is the interaction between propafenone and ritonavir?
The interaction is rated: Major. Evidence level: Moderate.
How is the interaction between propafenone and ritonavir managed?
Avoid or monitor closely with ECG.
Why do propafenone and ritonavir interact?
CYP3A4/2D6 inhibition.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.