Drug interactions

quetiapine + ritonavir

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Major · Evidence level: High

↑ quetiapine → coma/QT risk; avoid.

Mechanism of action

CYP3A4 inhibition.

Clinical management

Avoid or reduce dose significantly; monitor.

Drug reference

References

Frequently asked questions

Can I take quetiapine with ritonavir?

The interaction is rated: Major. ↑ quetiapine → coma/QT risk; avoid.

How serious is the interaction between quetiapine and ritonavir?

The interaction is rated: Major. Evidence level: High.

How is the interaction between quetiapine and ritonavir managed?

Avoid or reduce dose significantly; monitor.

Why do quetiapine and ritonavir interact?

CYP3A4 inhibition.

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