Drug interactions
Rifampicin + Tiratricol
Severity: Moderate
Rifampicin and Tiratricol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rifampicin is a potent enzyme inducer and can increase clearance of thyroid hormones and analogues. Reduced tiratricol effect and hypothyroid symptoms may follow.
What this interaction means in plain words
Rifampicin and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Rifampicin belongs to Anti Bacterial; Tiratricol belongs to Endocrine.
Why it happens
Rifampicin induces hepatic metabolizing enzymes, increasing tiratricol clearance.
What to do
Monitor T3 and clinical status during rifampicin therapy and increase the tiratricol dose if required. Reassess after rifampicin is stopped.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiratricol
- Levothyroxine + Tiratricol Major
- Calcium + Tiratricol Moderate
- Carbamazepine + Tiratricol Moderate
- Carbimazole + Tiratricol Moderate
- Charcoal + Tiratricol Moderate
- Chloroquine + Tiratricol Moderate
Other interactions of Rifampicin
- Cabotegravir + Rifampicin Contraindicated
- Delamanid + Rifampicin Contraindicated
- Doravirine + Rifampicin Contraindicated
- Ensitrelvir + Rifampicin Contraindicated
- Fostemsavir + Rifampicin Contraindicated
- Isavuconazole + Rifampicin Contraindicated
Frequently asked questions
Can I take Rifampicin with Tiratricol?
MediHelp rates the interaction as moderate. Rifampicin and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rifampicin is a potent enzyme inducer and can increase clearance of thyroid hormones and analogues. Reduced tiratricol effect and hypothyroid symptoms may follow.
How serious is the interaction between Rifampicin and Tiratricol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor T3 and clinical status during rifampicin therapy and increase the tiratricol dose if required. Reassess after rifampicin is stopped.
What other medicines interact with Tiratricol?
MediHelp also lists interactions of Tiratricol with, for example, Levothyroxine, Calcium, Carbamazepine. The full list is on the Tiratricol page.
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