Drug interactions
Sarecycline + Vinblastine
Severity: Minor
Sarecycline and Vinblastine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sarecycline has weak P-glycoprotein inhibition in vitro, and a clinically meaningful effect on vinblastine exposure is unlikely at usual doses. The interaction is mainly theoretical.
What this interaction means in plain words
Sarecycline and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Sarecycline belongs to Anti Bacterial; Vinblastine belongs to Oncology.
Why it happens
Possible weak P-glycoprotein inhibition reducing vinblastine efflux.
What to do
No routine adjustment is needed; monitor for vinblastine toxicity such as neutropenia or neuropathy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vinblastine
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Sarecycline with Vinblastine?
MediHelp rates the interaction as minor. Sarecycline and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sarecycline has weak P-glycoprotein inhibition in vitro, and a clinically meaningful effect on vinblastine exposure is unlikely at usual doses. The interaction is mainly theoretical.
How serious is the interaction between Sarecycline and Vinblastine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor for vinblastine toxicity such as neutropenia or neuropathy.
What other medicines interact with Vinblastine?
MediHelp also lists interactions of Vinblastine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Atazanavir. The full list is on the Vinblastine page.
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