Drug interactions
Sevelamer + Sotalol
Severity: Minor
Sevelamer and Sotalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sevelamer is a non-absorbed phosphate binder that can bind some oral drugs in the gut and reduce their absorption. A clinically meaningful effect on sotalol has not been well established, but a reduction in absorption is possible.
What this interaction means in plain words
Sevelamer and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Sevelamer belongs to Miscellaneous; Sotalol belongs to Cardiovascular.
Why it happens
Possible binding of sotalol in the gastrointestinal tract by sevelamer, reducing absorption; this is not well established.
What to do
Give sotalol at least 1 hour before or 3 hours after sevelamer, and monitor heart rate and rhythm control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Other interactions of Sevelamer
- Carbamazepine + Sevelamer Moderate
- Ciprofloxacin + Sevelamer Moderate
- Dichlorphenamide + Sevelamer Moderate
- Erdafitinib + Sevelamer Moderate
- Gabapentin + Sevelamer Moderate
- Mycophenolic acid + Sevelamer Moderate
Frequently asked questions
Can I take Sevelamer with Sotalol?
MediHelp rates the interaction as minor. Sevelamer and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sevelamer is a non-absorbed phosphate binder that can bind some oral drugs in the gut and reduce their absorption. A clinically meaningful effect on sotalol has not been well established, but a reduction in absorption is possible.
How serious is the interaction between Sevelamer and Sotalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give sotalol at least 1 hour before or 3 hours after sevelamer, and monitor heart rate and rhythm control.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
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