Drug interactions
Solifenacin + Telavancin
Severity: Moderate
Solifenacin and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telavancin has been associated with QT prolongation, and solifenacin may add to this effect. The risk is mainly relevant in patients with baseline QT prolongation, electrolyte disturbances or other proarrhythmic drugs.
What this interaction means in plain words
Solifenacin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Solifenacin belongs to Genitourinary; Telavancin belongs to Anti Bacterial.
Why it happens
Additive prolongation of cardiac repolarization.
What to do
Obtain an ECG and correct electrolytes before and during telavancin treatment in at-risk patients. Consider holding solifenacin during the antibiotic course if the QTc is markedly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Solifenacin
Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Frequently asked questions
Can I take Solifenacin with Telavancin?
MediHelp rates the interaction as moderate. Solifenacin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Telavancin has been associated with QT prolongation, and solifenacin may add to this effect. The risk is mainly relevant in patients with baseline QT prolongation, electrolyte disturbances or other proarrhythmic drugs.
How serious is the interaction between Solifenacin and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and correct electrolytes before and during telavancin treatment in at-risk patients. Consider holding solifenacin during the antibiotic course if the QTc is markedly prolonged.
What other medicines interact with Solifenacin?
MediHelp also lists interactions of Solifenacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Solifenacin page.
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