Drug interactions
Sotalol + Telmisartan-amlodipine
Severity: Moderate
Sotalol and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sotalol adds to the hypotensive and bradycardic effects of telmisartan and amlodipine. Hypotension can be more pronounced at initiation or after dose increases.
What this interaction means in plain words
Sotalol and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Sotalol belongs to Cardiovascular; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic antihypertensive effects of beta blockade with angiotensin receptor and calcium channel blockade.
What to do
Monitor blood pressure, heart rate and ECG when starting or adjusting therapy, and adjust doses if symptomatic hypotension or bradycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Frequently asked questions
Can I take Sotalol with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Sotalol and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sotalol adds to the hypotensive and bradycardic effects of telmisartan and amlodipine. Hypotension can be more pronounced at initiation or after dose increases.
How serious is the interaction between Sotalol and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and ECG when starting or adjusting therapy, and adjust doses if symptomatic hypotension or bradycardia occurs.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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