Drug interactions
Succinylcholine + Timolol
Severity: Minor
Succinylcholine and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic timolol can modestly impair cellular potassium uptake, but the effect on succinylcholine-induced hyperkalemia is minimal. Ophthalmic timolol may still be absorbed systemically, causing bradycardia in some patients.
What this interaction means in plain words
Succinylcholine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Succinylcholine belongs to Musculoskeletal; Timolol belongs to Cardiovascular.
Why it happens
Nonselective beta-blockade slightly impairs cellular potassium uptake, which could marginally add to the potassium rise from succinylcholine.
What to do
No routine change is needed. Monitor heart rate and potassium in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Succinylcholine and Timolol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Succinylcholine
Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Frequently asked questions
Can I take Succinylcholine with Timolol?
MediHelp rates the interaction as minor. Succinylcholine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic timolol can modestly impair cellular potassium uptake, but the effect on succinylcholine-induced hyperkalemia is minimal. Ophthalmic timolol may still be absorbed systemically, causing bradycardia in some patients.
How serious is the interaction between Succinylcholine and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor heart rate and potassium in patients with renal impairment.
What other medicines interact with Succinylcholine?
MediHelp also lists interactions of Succinylcholine with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Succinylcholine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
