Drug interactions
Tadalafil + Torsemide
Severity: Minor
Tadalafil and Torsemide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tadalafil may add to the blood pressure lowering of loop diuretics such as torsemide, particularly in volume-depleted patients. Symptomatic hypotension is possible.
What this interaction means in plain words
Tadalafil and Torsemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tadalafil belongs to Genitourinary; Torsemide belongs to Cardiovascular.
Why it happens
Additive hypotension from PDE5-mediated vasodilation and diuretic-induced volume depletion.
What to do
Monitor blood pressure and volume status after starting tadalafil. Counsel on dizziness on standing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tadalafil
- Amyl nitrite + Tadalafil Contraindicated
- Isosorbide dinitrate + Tadalafil Contraindicated
- Isosorbide mononitrate + Tadalafil Contraindicated
- Nitroglycerin po + Tadalafil Contraindicated
- Nitroglycerin rectal + Tadalafil Contraindicated
- Nitroglycerin sublingual + Tadalafil Contraindicated
Other interactions of Torsemide
Frequently asked questions
Can I take Tadalafil with Torsemide?
MediHelp rates the interaction as minor. Tadalafil and Torsemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tadalafil may add to the blood pressure lowering of loop diuretics such as torsemide, particularly in volume-depleted patients. Symptomatic hypotension is possible.
How serious is the interaction between Tadalafil and Torsemide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and volume status after starting tadalafil. Counsel on dizziness on standing.
What other medicines interact with Tadalafil?
MediHelp also lists interactions of Tadalafil with, for example, Amyl nitrite, Isosorbide dinitrate, Isosorbide mononitrate. The full list is on the Tadalafil page.
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