Drug interactions
Teicoplanin + Vancomycin
Severity: Moderate
Teicoplanin and Vancomycin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both glycopeptides can cause nephrotoxicity and, rarely, ototoxicity, and combining them offers no therapeutic benefit while adding risk. They are not normally prescribed together.
What this interaction means in plain words
Teicoplanin and Vancomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Teicoplanin belongs to Anti Bacterial; Vancomycin belongs to Anti Bacterial.
Why it happens
Additive nephrotoxicity and ototoxicity from two glycopeptide antibiotics.
What to do
Avoid concurrent use of both glycopeptides; choose one agent. If unavoidable, monitor renal function and drug levels and watch for hearing changes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Teicoplanin and Vancomycin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Vancomycin
- Amikacin + Vancomycin Major
- Bacitracin + Vancomycin Major
- Capreomycin + Vancomycin Major
- Cephaloridine + Vancomycin Major
- Cidofovir + Vancomycin Major
- Cisplatin + Vancomycin Major
Other interactions of Teicoplanin
- Amphotericin b + Teicoplanin Major
- Cidofovir + Teicoplanin Major
- Neomycin + Teicoplanin Major
- Teicoplanin + Tobramycin Major
- Acyclovir + Teicoplanin Moderate
- Adefovir + Teicoplanin Moderate
Frequently asked questions
Can I take Teicoplanin with Vancomycin?
MediHelp rates the interaction as moderate. Teicoplanin and Vancomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both glycopeptides can cause nephrotoxicity and, rarely, ototoxicity, and combining them offers no therapeutic benefit while adding risk. They are not normally prescribed together.
How serious is the interaction between Teicoplanin and Vancomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of both glycopeptides; choose one agent. If unavoidable, monitor renal function and drug levels and watch for hearing changes.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Bacitracin, Capreomycin. The full list is on the Vancomycin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
