Drug interactions
Telavancin + Voriconazole
Severity: Moderate
Telavancin and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole can prolong the QT interval and has been linked to torsades de pointes, and telavancin may add to this effect. The combination may increase arrhythmia risk, especially with electrolyte disturbance.
What this interaction means in plain words
Telavancin and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Telavancin belongs to Anti Bacterial; Voriconazole belongs to Anti Fungals.
Why it happens
Additive QTc prolongation.
What to do
Obtain baseline ECG and correct potassium, magnesium and calcium. Monitor the QTc during concurrent use and consider alternatives in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Telavancin with Voriconazole?
MediHelp rates the interaction as moderate. Telavancin and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voriconazole can prolong the QT interval and has been linked to torsades de pointes, and telavancin may add to this effect. The combination may increase arrhythmia risk, especially with electrolyte disturbance.
How serious is the interaction between Telavancin and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain baseline ECG and correct potassium, magnesium and calcium. Monitor the QTc during concurrent use and consider alternatives in high-risk patients.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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