Drug interactions
Telmisartan + Vadadustat
Severity: Minor
Telmisartan and Vadadustat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telmisartan may inhibit OAT1/OAT3 transporters involved in vadadustat elimination, which could raise vadadustat exposure. This may lead to an excessive rise in hemoglobin and related adverse effects.
What this interaction means in plain words
Telmisartan and Vadadustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Telmisartan belongs to Cardiovascular; Vadadustat belongs to Endocrine.
Why it happens
Possible inhibition of OAT1/OAT3-mediated renal transport reduces vadadustat clearance.
What to do
Monitor hemoglobin and adjust the vadadustat dose according to labeling if the rise is too rapid.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Vadadustat
- Atorvastatin + Vadadustat Moderate
- Balsalazide + Vadadustat Moderate
- Baricitinib + Vadadustat Moderate
- Benzathine penicillin g + Vadadustat Moderate
- Calcium carbonate + Vadadustat Moderate
- Calcium + Vadadustat Moderate
Frequently asked questions
Can I take Telmisartan with Vadadustat?
MediHelp rates the interaction as minor. Telmisartan and Vadadustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Telmisartan may inhibit OAT1/OAT3 transporters involved in vadadustat elimination, which could raise vadadustat exposure. This may lead to an excessive rise in hemoglobin and related adverse effects.
How serious is the interaction between Telmisartan and Vadadustat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and adjust the vadadustat dose according to labeling if the rise is too rapid.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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