Drug interactions
Terbutaline + Trazodone
Severity: Minor
Terbutaline and Trazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Trazodone is not a tricyclic and has weak effects on norepinephrine reuptake, so the legacy reuptake rationale does not apply well. Both drugs can cause tachycardia, hypotension or QT effects, giving a modest additive risk.
What this interaction means in plain words
Terbutaline and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Terbutaline belongs to Respiratory; Trazodone belongs to Central Nervous System.
Why it happens
Possible additive QT prolongation and hemodynamic effects; no established reuptake interaction.
What to do
No routine change needed; check potassium and consider an ECG in patients with cardiac disease or other QT-prolonging drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terbutaline
Other interactions of Trazodone
- Arsenic trioxide + Trazodone Contraindicated
- Ibutilide + Trazodone Contraindicated
- Isocarboxazid + Trazodone Contraindicated
- Levoketoconazole + Trazodone Contraindicated
- Methylene blue + Trazodone Contraindicated
- Phenelzine + Trazodone Contraindicated
Frequently asked questions
Can I take Terbutaline with Trazodone?
MediHelp rates the interaction as minor. Terbutaline and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Trazodone is not a tricyclic and has weak effects on norepinephrine reuptake, so the legacy reuptake rationale does not apply well. Both drugs can cause tachycardia, hypotension or QT effects, giving a modest additive risk.
How serious is the interaction between Terbutaline and Trazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change needed; check potassium and consider an ECG in patients with cardiac disease or other QT-prolonging drugs.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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