Drug interactions
Tolmetin + Vitamin k1
Severity: Minor
Tolmetin and Vitamin k1: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phytonadione promotes clotting factor synthesis and opposes anticoagulants, while tolmetin affects platelet function; there is no meaningful direct interaction between the two. Any bleeding concern comes from NSAIDs with anticoagulants, not from vitamin K.
What this interaction means in plain words
Tolmetin and Vitamin k1 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tolmetin belongs to Musculoskeletal; Vitamin k1 belongs to Cardiovascular.
Why it happens
No established interaction mechanism; the agents act on separate parts of hemostasis.
What to do
No specific action is needed; monitor INR and bleeding signs if the patient is also on a vitamin K antagonist.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Other interactions of Vitamin k1
- Vitamin k1 + Warfarin Major
- Cholestyramine + Vitamin k1 Moderate
- Colestipol + Vitamin k1 Moderate
- Ketorolac intranasal + Vitamin k1 Moderate
- Mineral oil + Vitamin k1 Moderate
- Orlistat + Vitamin k1 Moderate
Frequently asked questions
Can I take Tolmetin with Vitamin k1?
MediHelp rates the interaction as minor. Tolmetin and Vitamin k1 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phytonadione promotes clotting factor synthesis and opposes anticoagulants, while tolmetin affects platelet function; there is no meaningful direct interaction between the two. Any bleeding concern comes from NSAIDs with anticoagulants, not from vitamin K.
How serious is the interaction between Tolmetin and Vitamin k1?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor INR and bleeding signs if the patient is also on a vitamin K antagonist.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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