Drug interactions
Triptorelin + Voriconazole
Severity: Moderate
Triptorelin and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen deprivation therapy with triptorelin can prolong the QT interval, and voriconazole has the same effect. Together they may increase the risk of torsades de pointes, particularly with other risk factors.
What this interaction means in plain words
Triptorelin and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Triptorelin belongs to Endocrine; Voriconazole belongs to Anti Fungals.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Check baseline and follow-up ECGs and keep potassium and magnesium within normal range. Review other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Other interactions of Triptorelin
Frequently asked questions
Can I take Triptorelin with Voriconazole?
MediHelp rates the interaction as moderate. Triptorelin and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgen deprivation therapy with triptorelin can prolong the QT interval, and voriconazole has the same effect. Together they may increase the risk of torsades de pointes, particularly with other risk factors.
How serious is the interaction between Triptorelin and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline and follow-up ECGs and keep potassium and magnesium within normal range. Review other QT-prolonging drugs.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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