Drug interactions
Umeclidinium-vilanterol + Vardenafil
Severity: Minor
Umeclidinium-vilanterol and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vardenafil can produce small QT prolongation, and vilanterol may add cardiac stimulation. The combined clinical risk is low in most patients.
What this interaction means in plain words
Umeclidinium-vilanterol and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Umeclidinium-vilanterol belongs to Respiratory; Vardenafil belongs to Genitourinary.
Why it happens
Possible additive effects on cardiac repolarization.
What to do
No routine action is needed; consider ECG monitoring in patients with other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Umeclidinium-vilanterol
Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Umeclidinium-vilanterol with Vardenafil?
MediHelp rates the interaction as minor. Umeclidinium-vilanterol and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vardenafil can produce small QT prolongation, and vilanterol may add cardiac stimulation. The combined clinical risk is low in most patients.
How serious is the interaction between Umeclidinium-vilanterol and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; consider ECG monitoring in patients with other QT risk factors.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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