تداخل‌های دارویی
Cefazolin + Streptomycin
شدت: متوسط
Cefazolin and Streptomycin: moderate interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Combining cefazolin with streptomycin may increase the chance of renal injury, particularly in patients with reduced kidney function or dehydration. Streptomycin itself carries vestibular and cochlear toxicity, so any added renal impairment can raise drug exposure and worsen ototoxicity.
معنای این تداخل به زبان ساده
Cefazolin and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefazolin belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive nephrotoxic potential; reduced renal clearance of streptomycin can increase its toxicity.
اقدام لازم
Monitor renal function and streptomycin levels, and assess hearing and balance during therapy. Adjust the streptomycin dose for renal function.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefazolin و Streptomycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cefazolin
تداخلات دیگر Streptomycin
پرسش‌های متداول
Can I take Cefazolin with Streptomycin?
MediHelp rates the interaction as moderate. Cefazolin and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining cefazolin with streptomycin may increase the chance of renal injury, particularly in patients with reduced kidney function or dehydration. Streptomycin itself carries vestibular and cochlear toxicity, so any added renal impairment can raise drug exposure and worsen ototoxicity.
How serious is the interaction between Cefazolin and Streptomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and streptomycin levels, and assess hearing and balance during therapy. Adjust the streptomycin dose for renal function.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
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