تداخل‌های دارویی
Eletriptan + Idelalisib
شدت: منع مصرف
Eletriptan and Idelalisib: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Idelalisib is a strong CYP3A inhibitor and markedly increases exposure to CYP3A4 substrates. Eletriptan is labeled as contraindicated with strong CYP3A4 inhibitors within at least 72 hours because of the risk of higher exposure and vasoconstrictive adverse effects.
معنای این تداخل به زبان ساده
Eletriptan and Idelalisib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eletriptan belongs to Central Nervous System; Idelalisib belongs to Oncology.
چرا رخ می‌دهد
Strong CYP3A4 inhibition by idelalisib reduces eletriptan first-pass and systemic clearance.
اقدام لازم
Do not use eletriptan with idelalisib. Choose a triptan not metabolized by CYP3A4.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Eletriptan و Idelalisib، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Eletriptan
- Almotriptan + Eletriptan منع مصرف
- Atazanavir + Eletriptan منع مصرف
- Ceritinib + Eletriptan منع مصرف
- Clarithromycin + Eletriptan منع مصرف
- Cobicistat + Eletriptan منع مصرف
- Conivaptan + Eletriptan منع مصرف
تداخلات دیگر Idelalisib
- Alfuzosin + Idelalisib منع مصرف
- Cisapride + Idelalisib منع مصرف
- Dihydroergotamine + Idelalisib منع مصرف
- Dronedarone + Idelalisib منع مصرف
- Eplerenone + Idelalisib منع مصرف
- Ergotamine + Idelalisib منع مصرف
پرسش‌های متداول
Can I take Eletriptan with Idelalisib?
MediHelp rates the interaction as contraindicated. Eletriptan and Idelalisib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Idelalisib is a strong CYP3A inhibitor and markedly increases exposure to CYP3A4 substrates. Eletriptan is labeled as contraindicated with strong CYP3A4 inhibitors within at least 72 hours because of the risk of higher exposure and vasoconstrictive adverse effects.
How serious is the interaction between Eletriptan and Idelalisib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use eletriptan with idelalisib. Choose a triptan not metabolized by CYP3A4.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
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