تداخل‌های دارویی
Griseofulvin + Thalidomide
شدت: شدید
Griseofulvin and Thalidomide: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Griseofulvin induces hepatic enzymes and can lower hormonal contraceptive exposure, which matters because thalidomide is a potent teratogen requiring highly reliable contraception. The interaction is with the contraceptive rather than with thalidomide itself.
معنای این تداخل به زبان ساده
Griseofulvin and Thalidomide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Griseofulvin belongs to Anti Fungals; Thalidomide belongs to Miscellaneous.
چرا رخ می‌دهد
Enzyme induction by griseofulvin accelerates contraceptive hormone metabolism, reducing contraceptive efficacy.
اقدام لازم
In women of childbearing potential, do not rely on hormonal contraception alone during and for a period after griseofulvin; use an additional barrier method or a non-hormonal highly effective method such as an IUD.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Griseofulvin و Thalidomide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Thalidomide
تداخلات دیگر Griseofulvin
پرسش‌های متداول
Can I take Griseofulvin with Thalidomide?
MediHelp rates the interaction as major. Griseofulvin and Thalidomide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Griseofulvin induces hepatic enzymes and can lower hormonal contraceptive exposure, which matters because thalidomide is a potent teratogen requiring highly reliable contraception. The interaction is with the contraceptive rather than with thalidomide itself.
How serious is the interaction between Griseofulvin and Thalidomide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: In women of childbearing potential, do not rely on hormonal contraception alone during and for a period after griseofulvin; use an additional barrier method or a non-hormonal highly effective method such as an IUD.
What other medicines interact with Thalidomide?
MediHelp also lists interactions of Thalidomide with, for example, Bortezomib, Carbamazepine, Modafinil. The full list is on the Thalidomide page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
