Référentiel des médicaments
Interferon beta 1b
Interferon beta 1b is a medicine in the class central nervous system. It is used for multiple sclerosis.
- Classe médicamenteuse: Central Nervous System
- Indications: multiple sclerosis
Dernière mise à jour
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L'essentiel
- Classe médicamenteuse
- Central Nervous System
- Code ATC
- L03AB08
- Interactions connues
- 20 (Majeure: 11 · Modérée: 9)
- Noms commerciaux
- 1
- Pays et marchés
- 1
Indications
Mécanisme d'action
Recombinant interferon; antiviral, antiproliferative, immunoregulatory protein; alters response to surface antigen and may inhance immune cell activities
Posologie adulte habituelle (résumé de la notice)
0.0625 mg SC every other day initially
Grossesse et allaitement
- Grossesse
- Safe Registry data (over 1000 pregnancies) show no rise in major birth defects; it caused miscarriage in monkeys at about 3 times the human dose, but human data do not show a clear increase. EU label: may be considered in pregnancy if clinically needed.
- Allaitement
- Safe Interferon beta levels in milk are negligible and it is poorly absorbed by mouth. EU label: Betaferon can be used while breastfeeding; no harm to the infant is expected. LactMed: interferon beta is a preferred MS treatment during breastfeeding.
Effets indésirables signalés
- Headache
- Nausea
- Injection site reaction
- Fever
- Chills
- Flu-like syndrome
Précautions particulières
- To reduce injection site reactions; Bring a drug to room temperature before injection, Ice the injection site, and Rotate injection sites.
- Leukopenia may occur; monitor complete blood count
- Depression and suicide reported with increased frequency in patients receiving interferon beta products, including interferon beta-1b;
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
Principales interactions (20)
- Axicabtagene ciloleucel + Interferon beta 1b Major
- Brexucabtagene autoleucel + Interferon beta 1b Major
- Ciltacabtagene autoleucel + Interferon beta 1b Major
- Deferiprone + Interferon beta 1b Major
- Etrasimod + Interferon beta 1b Major
- Idecabtagene vicleucel + Interferon beta 1b Major
- Interferon beta 1b + Lisocabtagene maraleucel Major
- Interferon beta 1b + Pexidartinib Major
- Interferon beta 1b + Pretomanid Major
- Interferon beta 1b + Ropeginterferon alfa 2b Major
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
- IV preparation and dilution
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Questions fréquentes
What is Interferon beta 1b used for?
Interferon beta 1b is a medicine in the class central nervous system. It is used for Multiple sclerosis.
What side effects have been reported with Interferon beta 1b?
Headache, Nausea, Injection site reaction, Fever, Chills, Flu-like syndrome.
Can Interferon beta 1b be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Registry data (over 1000 pregnancies) show no rise in major birth defects; it caused miscarriage in monkeys at about 3 times the human dose, but human data do not show a clear increase. EU label: may be considered in pregnancy if clinically needed. Breastfeeding: Safe. Interferon beta levels in milk are negligible and it is poorly absorbed by mouth. EU label: Betaferon can be used while breastfeeding; no harm to the infant is expected. LactMed: interferon beta is a preferred MS treatment during breastfeeding.
What does Interferon beta 1b interact with?
MediHelp lists 20 known interactions for Interferon beta 1b. Major: 11 · Moderate: 9. The most serious include Axicabtagene ciloleucel, Brexucabtagene autoleucel, Ciltacabtagene autoleucel.
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