Interactions médicamenteuses
Antithymocyte globulin equine + Human papillomavirus vaccine
Gravité: Modérée
Antithymocyte globulin equine and Human papillomavirus vaccine: moderate interaction.
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Résumé
Equine antithymocyte globulin depletes T lymphocytes and causes profound immunosuppression, which can blunt the antibody response to HPV vaccination. Vaccine-induced protection may therefore be incomplete or short-lived.
Ce que signifie cette interaction, en termes simples
Antithymocyte globulin equine and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
T-cell depletion by the antithymocyte globulin impairs the immune response to the inactivated vaccine.
Conduite à tenir
Give HPV vaccine before starting antithymocyte globulin when feasible. If vaccinated during or soon after treatment, consider revaccination or antibody assessment once immune recovery has occurred.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Human papillomavirus vaccine
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Modérée
- Atidarsagene autotemcel + Human papillomavirus vaccine Modérée
- Belimumab + Human papillomavirus vaccine Modérée
- Cortisone + Human papillomavirus vaccine Modérée
- Cyclosporine + Human papillomavirus vaccine Modérée
- Elivaldogene autotemcel + Human papillomavirus vaccine Modérée
Questions fréquentes
Can I take Antithymocyte globulin equine with Human papillomavirus vaccine?
MediHelp rates the interaction as moderate. Antithymocyte globulin equine and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Equine antithymocyte globulin depletes T lymphocytes and causes profound immunosuppression, which can blunt the antibody response to HPV vaccination. Vaccine-induced protection may therefore be incomplete or short-lived.
How serious is the interaction between Antithymocyte globulin equine and Human papillomavirus vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give HPV vaccine before starting antithymocyte globulin when feasible. If vaccinated during or soon after treatment, consider revaccination or antibody assessment once immune recovery has occurred.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin rabbit, Atidarsagene autotemcel, Belimumab. The full list is on the Human papillomavirus vaccine page.
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