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Interactions médicamenteuses

Cortisone + Human papillomavirus vaccine

Gravité: Modérée

Cortisone and Human papillomavirus vaccine: moderate interaction.

Dernière mise à jour

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Résumé

Systemic corticosteroids at higher than physiologic doses suppress immune function and may reduce the antibody response to vaccines. Protection after HPV vaccination may be lower in patients on sustained high-dose therapy.

Ce que signifie cette interaction, en termes simples

Cortisone and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Glucocorticoid-mediated suppression of lymphocyte function reduces vaccine immunogenicity.

Conduite à tenir

Non-live HPV vaccine can be given to patients on corticosteroids. Where possible vaccinate when the dose is low or before starting prolonged high-dose therapy, and consider checking response.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Cortisone with Human papillomavirus vaccine?

MediHelp rates the interaction as moderate. Cortisone and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids at higher than physiologic doses suppress immune function and may reduce the antibody response to vaccines. Protection after HPV vaccination may be lower in patients on sustained high-dose therapy.

How serious is the interaction between Cortisone and Human papillomavirus vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Non-live HPV vaccine can be given to patients on corticosteroids. Where possible vaccinate when the dose is low or before starting prolonged high-dose therapy, and consider checking response.

What other medicines interact with Human papillomavirus vaccine?

MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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