Interactions médicamenteuses
Belimumab + Human papillomavirus vaccine
Gravité: Modérée
Belimumab and Human papillomavirus vaccine: moderate interaction.
Dernière mise à jour
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Résumé
Belimumab suppresses B-cell survival and may blunt the antibody response to HPV vaccination. Protection may therefore be lower than expected, although the vaccine is non-live and not unsafe.
Ce que signifie cette interaction, en termes simples
Belimumab and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Belimumab belongs to Miscellaneous; Human papillomavirus vaccine belongs to Miscellaneous.
Pourquoi elle survient
Pharmacodynamic antagonism: belimumab inhibits BLyS and reduces B-cell mediated humoral immune responses.
Conduite à tenir
Where possible, complete HPV vaccination before starting belimumab. If given during therapy, do not withhold the vaccine, and consider checking response or revaccinating when immunosuppression is reduced.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Modérée
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Modérée
- Atidarsagene autotemcel + Human papillomavirus vaccine Modérée
- Cortisone + Human papillomavirus vaccine Modérée
- Cyclosporine + Human papillomavirus vaccine Modérée
- Elivaldogene autotemcel + Human papillomavirus vaccine Modérée
Autres interactions de Belimumab
- Belimumab + Measles mumps and rubella vaccine Majeure
- Abatacept + Belimumab Modérée
- Adalimumab + Belimumab Modérée
- Anakinra + Belimumab Modérée
- Anti-thymocyte + Belimumab Modérée
- Belimumab + Denosumab Modérée
Questions fréquentes
Can I take Belimumab with Human papillomavirus vaccine?
MediHelp rates the interaction as moderate. Belimumab and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belimumab suppresses B-cell survival and may blunt the antibody response to HPV vaccination. Protection may therefore be lower than expected, although the vaccine is non-live and not unsafe.
How serious is the interaction between Belimumab and Human papillomavirus vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, complete HPV vaccination before starting belimumab. If given during therapy, do not withhold the vaccine, and consider checking response or revaccinating when immunosuppression is reduced.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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