Interactions médicamenteuses
Aztreonam + Cefpirome
Gravité: Mineure
Aztreonam and Cefpirome: minor interaction.
Dernière mise à jour
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Résumé
Aztreonam and cefpirome are both beta-lactam antibiotics with activity against gram-negative bacteria, and the combination can show additive or synergistic killing of some Enterobacteriaceae in vitro. This is generally a therapeutic benefit rather than a harmful interaction, though both drugs can cause hypersensitivity reactions and cross-reactivity is possible with cephalosporins with similar side chains.
Ce que signifie cette interaction, en termes simples
Aztreonam and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aztreonam belongs to Anti Bacterial; Cefpirome belongs to Anti Bacterial.
Pourquoi elle survient
Additive pharmacodynamic effect through binding of different penicillin-binding proteins in gram-negative bacteria.
Conduite à tenir
No routine adjustment is needed; use only when the combined spectrum is clinically intended and guided by culture results. Monitor for hypersensitivity reactions.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Autres interactions de Aztreonam
Autres interactions de Cefpirome
- Amikacin + Cefpirome Modérée
- Bupropion-naltrexone + Cefpirome Modérée
- Bupropion + Cefpirome Modérée
- Cefpirome + Dexamethasone-tobramycin Modérée
- Cefpirome + Gentamicin Modérée
- Cefpirome + Streptomycin Modérée
Questions fréquentes
Can I take Aztreonam with Cefpirome?
MediHelp rates the interaction as minor. Aztreonam and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aztreonam and cefpirome are both beta-lactam antibiotics with activity against gram-negative bacteria, and the combination can show additive or synergistic killing of some Enterobacteriaceae in vitro. This is generally a therapeutic benefit rather than a harmful interaction, though both drugs can cause hypersensitivity reactions and cross-reactivity is possible with cephalosporins with similar side chains.
How serious is the interaction between Aztreonam and Cefpirome?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; use only when the combined spectrum is clinically intended and guided by culture results. Monitor for hypersensitivity reactions.
What other medicines interact with Aztreonam?
MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Microbiota. The full list is on the Aztreonam page.
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