Interactions médicamenteuses
Bazedoxifene-conjugated estrogens + Ospemifene
Gravité: Contre-indiquée
Bazedoxifene-conjugated estrogens and Ospemifene: contraindicated interaction.
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Résumé
Both are estrogen agonist/antagonist agents with estrogenic effects on the endometrium and venous thromboembolism risk. Combining them adds duplicate therapy and additive risk of thromboembolic events and endometrial effects without benefit.
Ce que signifie cette interaction, en termes simples
Bazedoxifene-conjugated estrogens and Ospemifene are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Bazedoxifene-conjugated estrogens belongs to Endocrine; Ospemifene belongs to Endocrine.
Pourquoi elle survient
Additive pharmacodynamic estrogen-receptor modulation with duplicated prothrombotic and endometrial effects.
Conduite à tenir
Do not use together; choose one agent for menopausal symptoms.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Bazedoxifene-conjugated estrogens
- Anastrozole + Bazedoxifene-conjugated estrogens Contre-indiquée
- Antithrombin alfa + Bazedoxifene-conjugated estrogens Majeure
- Antithrombin iii + Bazedoxifene-conjugated estrogens Majeure
- Bazedoxifene-conjugated estrogens + Bemiparin Majeure
- Bazedoxifene-conjugated estrogens + Carbamazepine Majeure
- Bazedoxifene-conjugated estrogens + Dalteparin Majeure
Autres interactions de Ospemifene
- Estradiol + Ospemifene Contre-indiquée
- Clomiphene + Ospemifene Majeure
- Fluconazole + Ospemifene Majeure
- Ketoconazole + Ospemifene Majeure
- Ospemifene + Raloxifene Majeure
- Ospemifene + Rifampicin Majeure
Questions fréquentes
Can I take Bazedoxifene-conjugated estrogens with Ospemifene?
MediHelp rates the interaction as contraindicated. Bazedoxifene-conjugated estrogens and Ospemifene are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both are estrogen agonist/antagonist agents with estrogenic effects on the endometrium and venous thromboembolism risk. Combining them adds duplicate therapy and additive risk of thromboembolic events and endometrial effects without benefit.
How serious is the interaction between Bazedoxifene-conjugated estrogens and Ospemifene?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose one agent for menopausal symptoms.
What other medicines interact with Bazedoxifene-conjugated estrogens?
MediHelp also lists interactions of Bazedoxifene-conjugated estrogens with, for example, Anastrozole, Antithrombin alfa, Antithrombin iii. The full list is on the Bazedoxifene-conjugated estrogens page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
