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Interactions médicamenteuses

Benazepril + Isosorbide dinitrate

Gravité: Modérée

Benazepril and Isosorbide dinitrate: moderate interaction.

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Résumé

Nitrates cause venous and arterial dilation, and combining them with an ACE inhibitor can lower blood pressure further. This is often used intentionally but may cause symptomatic hypotension, especially at initiation.

Ce que signifie cette interaction, en termes simples

Benazepril and Isosorbide dinitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Benazepril belongs to Cardiovascular; Isosorbide dinitrate belongs to Cardiovascular.

Niveau de preuve: High

Pourquoi elle survient

Additive vasodilatory and hypotensive effects.

Conduite à tenir

Monitor blood pressure and orthostatic symptoms when starting or increasing either drug. Adjust doses if symptomatic hypotension occurs.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Benazepril with Isosorbide dinitrate?

MediHelp rates the interaction as moderate. Benazepril and Isosorbide dinitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nitrates cause venous and arterial dilation, and combining them with an ACE inhibitor can lower blood pressure further. This is often used intentionally but may cause symptomatic hypotension, especially at initiation.

How serious is the interaction between Benazepril and Isosorbide dinitrate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when starting or increasing either drug. Adjust doses if symptomatic hypotension occurs.

What other medicines interact with Benazepril?

MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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