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Interactions médicamenteuses

Benzathine penicillin g + Cholera vaccine

Gravité: Modérée

Benzathine penicillin g and Cholera vaccine: moderate interaction.

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Résumé

The oral live attenuated cholera vaccine contains a live bacterial strain that may be killed by systemic antibiotics, reducing the immune response. Penicillin G activity against Vibrio cholerae may impair vaccine take.

Ce que signifie cette interaction, en termes simples

Benzathine penicillin g and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Antibacterial activity against the live attenuated vaccine strain reduces replication and immunogenicity.

Conduite à tenir

Do not give the vaccine to patients who have taken systemic antibiotics within the prior 14 days, per labeling. Delay vaccination until the antibiotic course is finished.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Benzathine penicillin g with Cholera vaccine?

MediHelp rates the interaction as moderate. Benzathine penicillin g and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine contains a live bacterial strain that may be killed by systemic antibiotics, reducing the immune response. Penicillin G activity against Vibrio cholerae may impair vaccine take.

How serious is the interaction between Benzathine penicillin g and Cholera vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine to patients who have taken systemic antibiotics within the prior 14 days, per labeling. Delay vaccination until the antibiotic course is finished.

What other medicines interact with Benzathine penicillin g?

MediHelp also lists interactions of Benzathine penicillin g with, for example, Microbiota, Omadacycline, Sodium picosulfate / magnesium oxide / anhydrous citric acid. The full list is on the Benzathine penicillin g page.

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