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Interactions médicamenteuses

Benzathine penicillin g + Microbiota

Gravité: Modérée

Benzathine penicillin g and Microbiota: moderate interaction.

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Résumé

Oral microbiota products contain live bacterial spores intended to recolonize the gut. Concurrent penicillin can act against them and reduce engraftment and effectiveness, although benzathine penicillin has a prolonged presence after injection.

Ce que signifie cette interaction, en termes simples

Benzathine penicillin g and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Antibacterial activity of penicillin against the live microbiota components reduces colonization (pharmacodynamic antagonism).

Conduite à tenir

Complete antibiotic therapy and wait at least 2 to 4 days before giving oral microbiota. Because benzathine penicillin persists for weeks, consider timing the product with this in mind.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Benzathine penicillin g with Microbiota?

MediHelp rates the interaction as moderate. Benzathine penicillin g and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores intended to recolonize the gut. Concurrent penicillin can act against them and reduce engraftment and effectiveness, although benzathine penicillin has a prolonged presence after injection.

How serious is the interaction between Benzathine penicillin g and Microbiota?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete antibiotic therapy and wait at least 2 to 4 days before giving oral microbiota. Because benzathine penicillin persists for weeks, consider timing the product with this in mind.

What other medicines interact with Benzathine penicillin g?

MediHelp also lists interactions of Benzathine penicillin g with, for example, Cholera vaccine, Omadacycline, Sodium picosulfate / magnesium oxide / anhydrous citric acid. The full list is on the Benzathine penicillin g page.

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