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Interactions médicamenteuses

Cabotegravir + Lamivudine

Gravité: Modérée

Cabotegravir and Lamivudine: moderate interaction.

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Résumé

Oral or injectable cabotegravir with rilpivirine is a complete regimen for HIV-1 and is not intended to be combined with other antiretrovirals. Adding lamivudine is generally unnecessary and is not an established regimen. There is no clear pharmacokinetic interaction.

Ce que signifie cette interaction, en termes simples

Cabotegravir and Lamivudine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cabotegravir belongs to Anti Virals; Lamivudine belongs to Anti Virals.

Niveau de preuve: Low

Pourquoi elle survient

No established pharmacokinetic interaction; the concern is use outside the approved complete regimen.

Conduite à tenir

Do not add lamivudine to cabotegravir plus rilpivirine unless an HIV specialist directs it. Choose one complete regimen.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Cabotegravir with Lamivudine?

MediHelp rates the interaction as moderate. Cabotegravir and Lamivudine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral or injectable cabotegravir with rilpivirine is a complete regimen for HIV-1 and is not intended to be combined with other antiretrovirals. Adding lamivudine is generally unnecessary and is not an established regimen. There is no clear pharmacokinetic interaction.

How serious is the interaction between Cabotegravir and Lamivudine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not add lamivudine to cabotegravir plus rilpivirine unless an HIV specialist directs it. Choose one complete regimen.

What other medicines interact with Lamivudine?

MediHelp also lists interactions of Lamivudine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Atidarsagene autotemcel, Betibeglogene autotemcel. The full list is on the Lamivudine page.

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