Aller au contenu

Interactions médicamenteuses

Caplacizumab + Tirofiban

Gravité: Majeure

Caplacizumab and Tirofiban: major interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Tirofiban and caplacizumab both impair platelet function by different mechanisms, increasing the risk of serious bleeding.

Ce que signifie cette interaction, en termes simples

Caplacizumab and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Caplacizumab belongs to Cardiovascular; Tirofiban belongs to Cardiovascular.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive inhibition of vWF-dependent platelet adhesion and GP IIb/IIIa-dependent aggregation.

Conduite à tenir

Avoid combining where possible; if necessary, monitor for bleeding and withhold caplacizumab if clinically significant bleeding occurs.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Caplacizumab et Tirofiban, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Caplacizumab with Tirofiban?

MediHelp rates the interaction as major. Caplacizumab and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tirofiban and caplacizumab both impair platelet function by different mechanisms, increasing the risk of serious bleeding.

How serious is the interaction between Caplacizumab and Tirofiban?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; if necessary, monitor for bleeding and withhold caplacizumab if clinically significant bleeding occurs.

What other medicines interact with Tirofiban?

MediHelp also lists interactions of Tirofiban with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Tirofiban page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter