Interactions médicamenteuses
Capreomycin + Pancuronium
Gravité: Majeure
Capreomycin and Pancuronium: major interaction.
Dernière mise à jour
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Résumé
Capreomycin has neuromuscular blocking activity and can potentiate and prolong pancuronium paralysis. This can cause delayed recovery and respiratory depression or apnea.
Ce que signifie cette interaction, en termes simples
Capreomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Capreomycin has curare-like neuromuscular blocking action that adds to nondepolarizing blockade.
Conduite à tenir
Avoid combining if possible; otherwise reduce pancuronium dose, monitor with train-of-four and keep ventilatory support available through recovery.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Pancuronium
- Amikacin + Pancuronium Majeure
- Bacitracin-neomycin-polymyxin + Pancuronium Majeure
- Clindamycin + Pancuronium Majeure
- Colistin + Pancuronium Majeure
- Dexamethasone-tobramycin + Pancuronium Majeure
- Gentamicin + Pancuronium Majeure
Questions fréquentes
Can I take Capreomycin with Pancuronium?
MediHelp rates the interaction as major. Capreomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin has neuromuscular blocking activity and can potentiate and prolong pancuronium paralysis. This can cause delayed recovery and respiratory depression or apnea.
How serious is the interaction between Capreomycin and Pancuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining if possible; otherwise reduce pancuronium dose, monitor with train-of-four and keep ventilatory support available through recovery.
What other medicines interact with Pancuronium?
MediHelp also lists interactions of Pancuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Clindamycin. The full list is on the Pancuronium page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
