Interactions médicamenteuses
Cefalexin + Plazomicin
Gravité: Modérée
Cefalexin and Plazomicin: moderate interaction.
Dernière mise à jour
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Résumé
Plazomicin is an aminoglycoside with labeled risks of nephrotoxicity and ototoxicity. Other agents that can impair renal function, including cephalosporins in some reports, may add to kidney injury and raise plazomicin exposure.
Ce que signifie cette interaction, en termes simples
Cefalexin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefalexin belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Pourquoi elle survient
Additive nephrotoxic potential, with reduced renal clearance increasing aminoglycoside accumulation and ototoxicity.
Conduite à tenir
Monitor serum creatinine and plazomicin concentrations, and adjust dosing to renal function per labeling. Watch for hearing loss, tinnitus or vestibular symptoms.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefalexin
- Amikacin + Cefalexin Modérée
- Avelumab + Cefalexin Modérée
- Balstilimab + Cefalexin Modérée
- Bcg vaccine live + Cefalexin Modérée
- Cefalexin + Cholera vaccine Modérée
- Cefalexin + Gentamicin Modérée
Autres interactions de Plazomicin
- Cefaclor + Plazomicin Modérée
- Cefadroxil + Plazomicin Modérée
- Cefazolin + Plazomicin Modérée
- Cefditoren + Plazomicin Modérée
- Cefepime + Plazomicin Modérée
- Cefixime + Plazomicin Modérée
Questions fréquentes
Can I take Cefalexin with Plazomicin?
MediHelp rates the interaction as moderate. Cefalexin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with labeled risks of nephrotoxicity and ototoxicity. Other agents that can impair renal function, including cephalosporins in some reports, may add to kidney injury and raise plazomicin exposure.
How serious is the interaction between Cefalexin and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations, and adjust dosing to renal function per labeling. Watch for hearing loss, tinnitus or vestibular symptoms.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
