Interactions médicamenteuses
Cefazolin + Plazomicin
Gravité: Modérée
Cefazolin and Plazomicin: moderate interaction.
Dernière mise à jour
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Résumé
Cefazolin given with plazomicin may add to the risk of kidney injury, and plazomicin carries its own risk of nephrotoxicity, ototoxicity and neuromuscular blockade. Impaired renal function would increase plazomicin exposure and toxicity.
Ce que signifie cette interaction, en termes simples
Cefazolin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefazolin belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Pourquoi elle survient
Additive nephrotoxic potential, with reduced aminoglycoside clearance if renal function declines.
Conduite à tenir
Monitor serum creatinine and plazomicin concentrations during combined use. Adjust the plazomicin dose to renal function and monitor for hearing or balance changes.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefazolin
- Amikacin + Cefazolin Modérée
- Bcg vaccine live + Cefazolin Modérée
- Cefazolin + Cholera vaccine Modérée
- Cefazolin + Dexamethasone-tobramycin Modérée
- Cefazolin + Gentamicin Modérée
- Cefazolin + Kanamycin Modérée
Autres interactions de Plazomicin
- Cefaclor + Plazomicin Modérée
- Cefadroxil + Plazomicin Modérée
- Cefalexin + Plazomicin Modérée
- Cefditoren + Plazomicin Modérée
- Cefepime + Plazomicin Modérée
- Cefixime + Plazomicin Modérée
Questions fréquentes
Can I take Cefazolin with Plazomicin?
MediHelp rates the interaction as moderate. Cefazolin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefazolin given with plazomicin may add to the risk of kidney injury, and plazomicin carries its own risk of nephrotoxicity, ototoxicity and neuromuscular blockade. Impaired renal function would increase plazomicin exposure and toxicity.
How serious is the interaction between Cefazolin and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations during combined use. Adjust the plazomicin dose to renal function and monitor for hearing or balance changes.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
