Interactions médicamenteuses
Ceftazidime + Gentamicin
Gravité: Modérée
Ceftazidime and Gentamicin: moderate interaction.
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Résumé
Combining a cephalosporin with an aminoglycoside may raise the risk of kidney injury, and gentamicin itself is nephrotoxic and ototoxic. The additive risk with ceftazidime is modest and mainly relevant in patients with renal impairment, older age or dehydration.
Ce que signifie cette interaction, en termes simples
Ceftazidime and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ceftazidime belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.
Pourquoi elle survient
Possible additive nephrotoxicity, with reduced renal function leading to higher aminoglycoside exposure and greater ototoxic potential.
Conduite à tenir
Monitor serum creatinine and gentamicin levels and adjust doses to renal function. Keep the patient hydrated and limit the duration of aminoglycoside therapy.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Ceftazidime
- Amikacin + Ceftazidime Modérée
- Ceftazidime + Cholera vaccine Modérée
- Ceftazidime + Dexamethasone-tobramycin Modérée
- Ceftazidime + Kanamycin Modérée
- Ceftazidime + Microbiota Modérée
- Ceftazidime + Plazomicin Modérée
Autres interactions de Gentamicin
- Cidofovir + Gentamicin Contre-indiquée
- Adefovir + Gentamicin Majeure
- Amikacin + Gentamicin Majeure
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Majeure
- Amphotericin b deoxycholate + Gentamicin Majeure
- Amphotericin b + Gentamicin Majeure
Questions fréquentes
Can I take Ceftazidime with Gentamicin?
MediHelp rates the interaction as moderate. Ceftazidime and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining a cephalosporin with an aminoglycoside may raise the risk of kidney injury, and gentamicin itself is nephrotoxic and ototoxic. The additive risk with ceftazidime is modest and mainly relevant in patients with renal impairment, older age or dehydration.
How serious is the interaction between Ceftazidime and Gentamicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and gentamicin levels and adjust doses to renal function. Keep the patient hydrated and limit the duration of aminoglycoside therapy.
What other medicines interact with Ceftazidime?
MediHelp also lists interactions of Ceftazidime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Ceftazidime page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
