Interactions médicamenteuses
Certolizumab pegol + Measles mumps and rubella vaccine live
Gravité: Contre-indiquée
Certolizumab pegol and Measles mumps and rubella vaccine live: contraindicated interaction.
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Résumé
MMR vaccine contains live attenuated viruses. Certolizumab-induced immunosuppression may allow disseminated vaccine virus infection and reduce the immune response.
Ce que signifie cette interaction, en termes simples
Certolizumab pegol and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
TNF inhibition impairs immune control of live attenuated viruses.
Conduite à tenir
Avoid MMR during certolizumab therapy. Complete live vaccination at least 4 weeks before starting, and check immunity serologically if exposure risk exists.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contre-indiquée
- Bcg intravesical live + Certolizumab pegol Contre-indiquée
- Bcg vaccine live + Certolizumab pegol Contre-indiquée
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine Contre-indiquée
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Certolizumab pegol with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR vaccine contains live attenuated viruses. Certolizumab-induced immunosuppression may allow disseminated vaccine virus infection and reduce the immune response.
How serious is the interaction between Certolizumab pegol and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid MMR during certolizumab therapy. Complete live vaccination at least 4 weeks before starting, and check immunity serologically if exposure risk exists.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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