Interactions médicamenteuses
Certolizumab pegol + Measles mumps rubella and varicella vaccine live
Gravité: Contre-indiquée
Certolizumab pegol and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
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Résumé
MMRV vaccine contains four live attenuated viruses. In patients on certolizumab, uncontrolled vaccine virus replication and disseminated disease can occur, and the immune response may be blunted.
Ce que signifie cette interaction, en termes simples
Certolizumab pegol and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
TNF inhibition suppresses immunity needed to control attenuated live viruses.
Conduite à tenir
Do not use MMRV during certolizumab therapy. Give it at least 4 weeks before starting treatment if possible.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contre-indiquée
- Bcg intravesical live + Certolizumab pegol Contre-indiquée
- Bcg vaccine live + Certolizumab pegol Contre-indiquée
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine live Contre-indiquée
Questions fréquentes
Can I take Certolizumab pegol with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMRV vaccine contains four live attenuated viruses. In patients on certolizumab, uncontrolled vaccine virus replication and disseminated disease can occur, and the immune response may be blunted.
How serious is the interaction between Certolizumab pegol and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use MMRV during certolizumab therapy. Give it at least 4 weeks before starting treatment if possible.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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